Details for gene set CL17474, PHOSPHATIDYLINOSITOL 3-KINASE COMPLEX, CLASS I, AND INSULIN RECEPTOR COMPLEX[GSEA]

Table: GSEA Results Summary

Dataset	Irritable bowel syndrome__20002-both_sexes-1154
Phenotype	NoPhenotypeAvailable
Upregulated in class	na_pos
GeneSet	CL17474, PHOSPHATIDYLINOSITOL 3-KINASE COMPLEX, CLASS I, AND INSULIN RECEPTOR COMPLEX
Enrichment Score (ES)	0.6207762
Normalized Enrichment Score (NES)	1.287802
Nominal p-value	0.08140703
FDR q-value	1.0
FWER p-Value	0.851

Fig 1: Enrichment plot: CL17474, PHOSPHATIDYLINOSITOL 3-KINASE COMPLEX, CLASS I, AND INSULIN RECEPTOR COMPLEX
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

Table: GSEA details [plain text format]
	SYMBOL	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	PIK3R3	158	2.283	0.2172	Yes
2	PIK3CB	807	1.422	0.3218	Yes
3	PTPN1	875	1.363	0.4529	Yes
4	IRS2	999	1.286	0.5734	Yes
5	PIK3R1	3527	0.621	0.4941	Yes
6	SOCS4	3972	0.560	0.5248	Yes
7	PIK3CA	4441	0.511	0.5494	Yes
8	IGF1R	4488	0.507	0.5970	Yes
9	PIK3R5	4887	0.464	0.6208	Yes
10	INSRR	7859	0.269	0.4819	No
11	PIK3CD	9568	0.200	0.4066	No
12	PIK3R2	9895	0.189	0.4071	No
13	IRS1	10625	0.164	0.3828	No
14	INSR	12840	0.108	0.2702	No
15	IRS4	13473	0.095	0.2444	No
16	INS	15341	0.061	0.1465	No
17	PIK3CG	16739	-0.000	0.0687	No
18	PIK3R6	17953	-0.000	0.0012	No

Fig 2: CL17474, PHOSPHATIDYLINOSITOL 3-KINASE COMPLEX, CLASS I, AND INSULIN RECEPTOR COMPLEX: Random ES distribution
Gene set null distribution of ES for CL17474, PHOSPHATIDYLINOSITOL 3-KINASE COMPLEX, CLASS I, AND INSULIN RECEPTOR COMPLEX